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METHADONE
METHADONE CONCENTRATE - ORAL

Important Note

The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

METHADONE CONCENTRATE - ORAL

(METH-uh-doan)

COMMON BRAND NAME(S): Methadose

WARNING: Methadone is to be taken by mouth only. It must not be injected. Methadone is a synthetic narcotic. Patients who are physically dependent on narcotics will go through withdrawal syndrome if given the usual dose of a narcotic antagonist (e.g., naloxone). If a narcotic antagonist must be given, the dose must be smaller than the usual dose and it must be given with extreme care.

Uses

This is used for narcotic addiction. Methadone is a potent narcotic substance. It can cause serious side effects and toxic reactions if used by someone other than the person for whom it is prescribed. Do not share this medication with others.

OTHER

Uses

This drug may also be used for severe pain.

How To Use

Take this medication only by mouth. To prevent upset stomach, take with food or milk. Take this as prescribed. Do not increase your dose, take it more frequently or use it for a longer period of time without your doctor's approval. Also, if used for a long period of time at high doses, do not suddenly stop taking this without first consulting your doctor. When used for extended periods, this medication may not work as well and may require different dosing. Consult your doctor if the medication isn't working properly.

Side Effects

May cause constipation, lightheadedness, dizziness, drowsiness, stomach upset, nausea, and flushing the first few days as your body adjusts to the medication. If these symptoms persist or become bothersome, inform your doctor. To minimize constipation, increase your intake of fiber, drink plenty of water, and exercise. Stool softeners may be helpful. Ask your doctor or pharmacist about stool softeners and laxatives. Notify your doctor if you develop: irregular heartbeats, anxiety, tremors, seizures. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor your medical history, especially of: stomach problems (e.g., colitis), substance abuse problems, allergies. Use caution engaging in activities requiring alertness such as driving or using machinery. Alcoholic beverages may add to the effects of this medication causing dizziness or drowsiness. Ask your doctor or pharmacist about the use of alcohol. Caution is advised when using this drug in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug is excreted into breast milk and may affect the infant. Consult your doctor before breast-feeding.

Drug Interactions

Tell your doctor of all prescription and nonprescription drugs you may be using, especially: MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, selegiline, tranylcypromine), psychiatric drugs, tranquilizers, sleeping pills, zidovudine, rifampin, other narcotic pain relievers, barbiturates, cimetidine, anti-seizure drugs, certain antihistamines (e.g., diphenhydramine), alcohol. Do not start or stop any medicine without doctor or pharmacist approval.

Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include cold and clammy skin, low body temperature, slowed breathing, slowed heartbeat, drowsiness, dizziness, lightheadedness, deep sleep, and loss of consciousness.

Notes

Do not share this medication with others. It is against the law.

Missed Dose

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Storage

Store at room temperature between 59 and 86 degrees F (between 15 and 30 degrees C) away from moisture and sunlight. Do not store in the bathroom.